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The Liverpool Ophthalmic Reading Centre (LORC) is part of St Paul's Eye Unit, Royal Liverpool University Hospital and is strongly linked with the research activity of the Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool.

Liverpool Ophthalmic Reading Centre

The Liverpool Ophthalmic Reading Centre was established in 2005 to support multi-centre clinical trials on eye diseases consisting of Age Related Macular Degeneration (AMD) and Diabetic Retinopathy and is linked to reading centres in Belfast and Moorfields, London. All three reading centres form the Network of Reading Centres UK (NetwORC UK) coordinated by the Central Angiographic Reading Centres (CARF) in Belfast.

In addition to its grading of Angiographic and Tomographic images for Age Related Macular Degeneration (AMD) and Diabetic Retinopathy for clinical trials, the Liverpool Ophthalmic Reading Centre also provides grading to local, national and international programmes, screening for sight threatening Diabetic Retinopathy.

Retinal Image Grading

Ophthalmic Grading consists of our highly trained Graders and Clinicians at the Liverpool Ophthalmic Reading Centre (LORC), reviewing various types of high quality photographic images and scans of the back of the eye (the retina) to allow us to objectively evaluate, classify and create detailed reports on two of the main causes of sight loss in the UK, Age Related Macular Degeneration (AMD) and Diabetic Retinopathy for ophthalmic research studies to confirm clinical diagnosis.

Image types we use

  • Stereo Colour Fundus Photography
  • Optical Coherence Tomography (OCT)
  • Fluorescein Angiography
  • Indocyanine Green Angiography

The Ophthalmic Image Graders in the LORC are externally accredited to perform grading of retinal images in commercial and grant funded studies.

Our Studies

In this section we aim to provide you with an overview of the studies we are working on currently or have worked on in the past.

The IVAN Trial

IVAN (A randomised controlled trial of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation)

The IVAN Trial Homepage

The MERLOT Study

MERLOT (Macular EpiRetinal Brachytherapy versus Lucentis Only Treatment)

The MERLOT Study Homepage

Who we are

The Liverpool Ophthalmic Reading Centre (LORC) is part of the Clinical Eye Research Centre at St Paul's Eye Unit and is strongly linked with the research from the Department of Eye and Vision Science at the University of Liverpool.

Established in 2005, LORC was created to support multi-centre clinical trials on eye diseases, including age-related macular degeneration (AMD), diabetic retinopathy and glaucoma. Our internationally-accredited graders review various types of high quality images and scans of the eye to allow us to evaluate, classify and create detailed reports for national and international clinical research studies. Our experienced clinicians provide support and quality assurance.

LORC is linked to reading centres in Belfast and Moorfields, London. All three reading centres form the Network of Reading Centres UK (NetwORC UK) coordinated by the Central Angiographic Reading Centre (CARF) in Belfast.

Image types we use include:

  • stereo colour fundus photography
  • optical coherence tomography (OCT)
  • fluorescein angiography
  • indocyanine green angiography
  • wide-field imaging
  • visual fields
  • autofluorescence

Contact us

Liverpool Ophthalmic Reading Centre
Room 349
3rd Floor, University Clinical Department
Royal Liverpool University Hospital
Prescot Street
Liverpool
L7 8XP

Contact: 0151 706 5377

Our team

Mrs Savitha Madhusudhan FRCOphth
Consultant Ophthalmologist
Director, Liverpool Ophthalmic Reading Centre

Dr Pauline Lenfestey, MRCOpth
Associate Specialist
Training and development lead, Liverpool Ophthalmic Reading Centre

Professor Simon Harding, FRCOphth, MD
Department of Eye and Vision Science, University of Liverpool

Mr David Parry
Senior Ophthalmic Image Grader

Sophie Leach
Ophthalmic Image Grader

Mrs Lindy Gee
Data Manager